For femoral arterial access, manual pressure is held just proximal to the skin entry point (over the actual arteriotomy, which is typically slightly proximal to the skin nick) for a duration based on sheath size and anticoagulation status — commonly 10–20 minutes minimum, longer if anticoagulated, with gradual release to check for rebleeding before fully releasing pressure. For radial access, a compression device (e.g., a band) is applied with patent hemostasis technique — maintaining radial artery patency (confirmed by pulse oximetry/plethysmography on the thumb) while still controlling bleeding at the puncture site.
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